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Depression is a mood disorder with variable duration that is common among the elderly and characterized by a chemical imbalance in the brain. Symptoms to watch for include insomnia, persistent sadness, disinterest in activities, loss of appetite, slow movement and speech, and drug or alcohol dependency. When constructing a treatment plan, consider the impact of the patient social, biological, psychological, genetic, and medical background. Caregivers can help alleviate the symptoms of depression by encouraging healthy eating, regular exercise, medication adherence, and providing meaningful social connections which have been shown to help individuals cope with depression. depression.